NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia

Bibliographic Details
Main Authors: Xibao Yu, Ardalan Mansouri, Zhuandi Liu, Rili Gao, Kehan Li, Cunte Chen, Youxue Huang, Zheng Chen, Shaohua Chen, Yuhong Lu, Yangqiu Li, Chengwu Zeng, Yixin Zeng
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Clinical and Translational Medicine
Online Access:https://doi.org/10.1002/ctm2.418
id doaj-52fe95545d27476ca01eaa177d1a5dea
record_format Article
spelling doaj-52fe95545d27476ca01eaa177d1a5dea2021-05-28T10:14:30ZengWileyClinical and Translational Medicine2001-13262021-05-01115n/an/a10.1002/ctm2.418NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemiaXibao Yu0Ardalan Mansouri1Zhuandi Liu2Rili Gao3Kehan Li4Cunte Chen5Youxue Huang6Zheng Chen7Shaohua Chen8Yuhong Lu9Yangqiu Li10Chengwu Zeng11Yixin Zeng12Department of Experimental Research Sun Yat‐Sen University Cancer Center, State Key Laboratory Oncology in South China Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaDepartment of Hematology First Affiliated Hospital, Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaKey Laboratory for Regenerative Medicine of Ministry of Education Institute of Hematology, School of Medicine Jinan University Guangzhou ChinaDepartment of Experimental Research Sun Yat‐Sen University Cancer Center, State Key Laboratory Oncology in South China Guangzhou Chinahttps://doi.org/10.1002/ctm2.418
collection DOAJ
language English
format Article
sources DOAJ
author Xibao Yu
Ardalan Mansouri
Zhuandi Liu
Rili Gao
Kehan Li
Cunte Chen
Youxue Huang
Zheng Chen
Shaohua Chen
Yuhong Lu
Yangqiu Li
Chengwu Zeng
Yixin Zeng
spellingShingle Xibao Yu
Ardalan Mansouri
Zhuandi Liu
Rili Gao
Kehan Li
Cunte Chen
Youxue Huang
Zheng Chen
Shaohua Chen
Yuhong Lu
Yangqiu Li
Chengwu Zeng
Yixin Zeng
NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia
Clinical and Translational Medicine
author_facet Xibao Yu
Ardalan Mansouri
Zhuandi Liu
Rili Gao
Kehan Li
Cunte Chen
Youxue Huang
Zheng Chen
Shaohua Chen
Yuhong Lu
Yangqiu Li
Chengwu Zeng
Yixin Zeng
author_sort Xibao Yu
title NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia
title_short NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia
title_full NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia
title_fullStr NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia
title_full_unstemmed NRF2 activation induced by PML‐RARα promotes microRNA 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia
title_sort nrf2 activation induced by pml‐rarα promotes microrna 125b‐1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia
publisher Wiley
series Clinical and Translational Medicine
issn 2001-1326
publishDate 2021-05-01
url https://doi.org/10.1002/ctm2.418
work_keys_str_mv AT xibaoyu nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT ardalanmansouri nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT zhuandiliu nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT riligao nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT kehanli nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT cuntechen nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT youxuehuang nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT zhengchen nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT shaohuachen nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT yuhonglu nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT yangqiuli nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT chengwuzeng nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
AT yixinzeng nrf2activationinducedbypmlrarapromotesmicrorna125b1expressionandconfersresistancetochemotherapyinacutepromyelocyticleukemia
_version_ 1721424209849090048