Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes

<p>Abstract</p> <p>Background</p> <p>Clarifying the physicochemical properties of nanomaterials is crucial for hazard assessment and the safe application of these substances. With this in mind, we analyzed the relationship between particle size and the <it>in vitr...

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Main Authors: Hirai Toshiro, Kondoh Sayuri, Tochigi Saeko, Nakazato Yasutaro, Matsuyama Keigo, Yoshikawa Tomoaki, Nabeshi Hiromi, Akase Takanori, Nagano Kazuya, Abe Yasuhiro, Yoshioka Yasuo, Kamada Haruhiko, Itoh Norio, Tsunoda Shin-ichi, Tsutsumi Yasuo
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Particle and Fibre Toxicology
Online Access:http://www.particleandfibretoxicology.com/content/8/1/1

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