Nucleocytoplasmic distribution of S6K1 depends on the density and motility of MCF-7 cells in vitro [version 2; referees: 2 approved]
Background: The ribosomal protein S6 kinase 1 (S6K1) is one of the main components of the mTOR/S6K signal transduction pathway, which controls cellular metabolism, autophagy, growth, and proliferation. Overexpression of S6K1 was detected in tumors of different origin including breast cancer, and cor...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2018-12-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/7-1332/v2 |