Nucleocytoplasmic distribution of S6K1 depends on the density and motility of MCF-7 cells in vitro [version 2; referees: 2 approved]

Background: The ribosomal protein S6 kinase 1 (S6K1) is one of the main components of the mTOR/S6K signal transduction pathway, which controls cellular metabolism, autophagy, growth, and proliferation. Overexpression of S6K1 was detected in tumors of different origin including breast cancer, and cor...

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Bibliographic Details
Main Authors: Viktoriia Kosach, Kateryna Shkarina, Anastasiia Kravchenko, Yuliia Tereshchenko, Evelina Kovalchuk, Larysa Skoroda, Mykhailo Krotevych, Antonina Khoruzhenko
Format: Article
Language:English
Published: F1000 Research Ltd 2018-12-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-1332/v2