Time-Frequency Characterization of Cerebral Hemodynamics of Migraine Sufferers as Assessed by NIRS Signals
<p>Abstract</p> <p>Near-infrared spectroscopy (NIRS) is a noninvasive system for the real-time monitoring of the concentration of oxygenated (<inline-formula> <graphic file="1687-6180-2010-459213-i1.gif"/></inline-formula>) and reduced (HHb) hemoglobin i...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2010-01-01
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| Series: | EURASIP Journal on Advances in Signal Processing |
| Online Access: | http://asp.eurasipjournals.com/content/2010/459213 |
| Summary: | <p>Abstract</p> <p>Near-infrared spectroscopy (NIRS) is a noninvasive system for the real-time monitoring of the concentration of oxygenated (<inline-formula> <graphic file="1687-6180-2010-459213-i1.gif"/></inline-formula>) and reduced (HHb) hemoglobin in the brain cortex. <inline-formula> <graphic file="1687-6180-2010-459213-i2.gif"/></inline-formula> and HHb concentrations vary in response to cerebral autoregulation. Sixty-eight women (14 migraineurs without aura, 49 migraineurs with aura, and 5 controls) performed breath-holding and hyperventilation during NIRS recordings. Signals were processed using the Choi-Williams time-frequency transform in order to measure the power variation of the very-low frequencies (VLF: 20–40 mHz) and of the low frequencies (LF: 40–140 mHz). Results showed that migraineurs without aura present different LF and VLF power levels than controls and migraineurs with aura. The accurate power measurement of the time-frequency analysis allowed for the discrimination of the subjects' hemodynamic patterns. The time-frequency analysis of NIRS signals can be used in clinical practice to assess cerebral hemodynamics.</p> |
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| ISSN: | 1687-6172 1687-6180 |