Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment
Abstract Photoreceptor death and neurodegeneration is the leading cause of irreversible vision loss. The inflammatory response of microglia plays an important role in the process of neurodegeneration. In this study, we chose retinal detachment as the model of photoreceptor degeneration. We found Myo...
Main Authors: | Yimin Wang, Xiaohuan Zhao, Min Gao, Xiaoling Wan, Yinong Guo, Yingying Qu, Yuhong Chen, Tong Li, Haiyun Liu, Mei Jiang, Feng Wang, Xiaodong Sun |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-10-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03983-3 |
Similar Items
-
Microglia are not required for prion-induced retinal photoreceptor degeneration
by: James F. Striebel, et al.
Published: (2019-03-01) -
Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa
by: Thomas Blank, et al.
Published: (2018-01-01) -
Microglia in Retinal Degeneration
by: Khalid Rashid, et al.
Published: (2019-08-01) -
Exosomes derived from neural progenitor cells preserve photoreceptors during retinal degeneration by inactivating microglia
by: Baishijiao Bian, et al.
Published: (2020-01-01) -
Activation of autophagy in photoreceptor necroptosis after experimental retinal detachment
by: Kai Dong, et al.
Published: (2014-10-01)