Proteinase-Mediated Macrophage Signaling in Psoriatic Arthritis

ObjectiveMultiple proteinases are present in the synovial fluid (SF) of an arthritic joint. We aimed to identify inflammatory cell populations present in psoriatic arthritis (PsA) SF compared to osteoarthritis (OA) and rheumatoid arthritis (RA), identify their proteinase-activated receptor 2 (PAR2)...

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Main Authors: Fatima Abji, Mozhgan Rasti, Alejandro Gómez-Aristizábal, Carla Muytjens, Mahmoud Saifeddine, Koichiro Mihara, Majid Motahhari, Rajiv Gandhi, Sowmya Viswanathan, Morley D. Hollenberg, Katerina Oikonomopoulou, Vinod Chandran
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.629726/full