The Proinflammatory and Proangiogenic Macrophage Migration Inhibitory Factor Is a Potential Regulator in Proliferative Diabetic Retinopathy

The Proinflammatory and Proangiogenic Macrophage Migration Inhibitory Factor Is a Potential Regulator in Proliferative Diabetic Retinopathy

The macrophage migration inhibitory factor (MIF)/CD74 signaling pathway is strongly implicated in inflammation and angiogenesis. We investigated the expression of MIF and its receptor CD74 in proliferative diabetic retinopathy (PDR) to reveal a possible role of this pathway in the pathogenesis of PD...

Full description

Bibliographic Details
Main Authors: Ahmed M. Abu El-Asrar, Ajmal Ahmad, Mohammad Mairaj Siddiquei, Alexandra De Zutter, Eef Allegaert, Priscilla W. Gikandi, Gert De Hertogh, Jo Van Damme, Ghislain Opdenakker, Sofie Struyf
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Immunology
Subjects:
proliferative diabetic retinopathy
migration inhibitory factor
CD74
angiogenesis
Müller cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02752/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02752/full

Similar Items