Patterns of Antimicrobial therapy in acute tonsillitis: A cross-sectional Hospital-based study from UAE

• Main Authors: LISHA J. JOHN, MEENU CHERIAN, JAYADEVAN SREEDHARAN, TAMBI CHERIAN
• Format: Article
• Language: English
• Published: Academia Brasileira de Ciências 2014-03-01
• Series: Anais da Academia Brasileira de Ciências
• Subjects: utilização de drogas; utilização antimicrobiana; amidalite aguda; parenteral
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000100451&lng=en&tlng=en
• ISSN: 1678-2690

Background: Diseases of the ear, nose and throat (ENT) are associated with significant impairment of the daily life and a major cause for absenteeism from work. Aim: The study determined antimicrobial prescription pattern in patients with acute tonsillitis. Materials and Methods: A cross-sectional study was carried out among all the patients attending the ENT department with acute tonsillitis. Data were retrieved from the medical records using a proforma. Statistical analysis was carried out using SPSS.19. Results: Total of 238 patients included (Males 138; females 100). About 96% of total drugs were prescribed by generic name. Median number of drugs prescribed was four (range 1-7). Eighty eight percent of prescriptions contained antimicrobials, (78.5%) analgesics and (57.9%) antipyretics. Amoxicillin / Clavulanic acid (24.8%) and Ceftriaxone (12.2%) were the most commonly prescribed antimicrobials. Parenteral route was preferred in 41.6%. About 23.7% of the patients on Amoxicillin / Clavulanic acid had received the drug as intravenous injection. Culture and sensitivity tests were carried out in 106 (44.5%) of the cases. Antimicrobials were changed / added after the culture and sensitivity test in 25 patients. Conclusion: Study findings highlighted rational practices in drug prescribing. Therapeutic guidelines based on current sensitivity pattern optimize the use of antimicrobial agents.