Small DNA pieces in C. elegans are intermediates of DNA fragmentation during apoptosis.

Small DNA pieces in C. elegans are intermediates of DNA fragmentation during apoptosis.

While studying small noncoding RNA in C. elegans, we discovered that protocols used for isolation of RNA are contaminated with small DNA pieces. After electrophoresis on a denaturing gel, the DNA fragments appear as a ladder of bands, approximately 10 nucleotides apart, mimicking the pattern of nucl...

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Bibliographic Details
Main Authors: P Joseph Aruscavage, Sabine Hellwig, Brenda L Bass
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2887891?pdf=render

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