Orbital malignant melanoma associated with nevus of Ota

• Main Authors: Cherungottil V Radhadevi, Kakkuzhiyil S Charles, Vasu K Lathika
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2013-01-01
• Series: Indian Journal of Ophthalmology
• Subjects: Algorithmic approach; differential diagnosis; naming and meshing; uveitis; Uveitis; imaging; fluorescein angiography; optical coherence tomography; Angiotensin converting enzyme; antitoxoplasma antibody; laboratory test; tuberculin test; Corticosteroids; immunosuppressives; medical management; Cataract surgery in uveitis; glaucoma surgery in uveitis; vitrectomy in uveitis; Sarcoidosis; choroidal nodules; Central India; conjunctivitis; Oestrus ovis; Ophthalmomyiasis; Acute retinal necrosis; ocular toxoplasmosis; polymerase chain reaction; scleritis; Magnetic resonance imaging; ocular dirofilariasis; ultrasound; Acanthamoeba; Acanthamoeba sclerokeratitis; granulomatous inflammation; immunosuppressive agents; T cells; immunosuppression; serpiginous choroiditis; Bevacizumab; choroid; choroidal neovascularization; choroidal nevus; nevus; Malignant melanoma; nevus of Ota; orbitotomy
• Online Access: http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=6;spage=306;epage=309;aulast=Radhadevi

Nevus of Ota (oculodermal melanosis) is a dermal melanocytic hamartoma with bluish hyperpigmentation along the first and second branches of the trigeminal nerve. Extracutaneous involvement, especially ocular, has been reported. A 45-year-old male presented with malignant melanoma of the left orbit in association with nevus of Ota. Being locally invasive, a modified exenteration with frontal flap repair was done on left eye. Adjuvant chemotherapy was given after wound healing. All pigmented lesions of the eye require close monitoring to help in the early diagnosis. Since malignant transformation has been reported in oculodermal melanosis, close follow-up and patient education will facilitate early diagnosis and prompt management. This case is reported for its rarity and unusual presentation.