Concomitant Nrf2- and ATF4-Activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes

Concomitant Nrf2- and ATF4-Activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes

Carnosic acid (CA) is a phytochemical found in some dietary herbs, such as <i>Rosmarinus officinalis</i> L., and possesses antioxidative and anti-microbial properties. We previously demonstrated that CA functions as an activator of nuclear factor, erythroid 2 (NF-E2)-related factor 2 (Nr...

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Bibliographic Details
Main Authors: Junsei Mimura, Atsushi Inose-Maruyama, Shusuke Taniuchi, Kunio Kosaka, Hidemi Yoshida, Hiromi Yamazaki, Shuya Kasai, Nobuhiko Harada, Randal J. Kaufman, Seiichi Oyadomari, Ken Itoh
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
Nrf2
ATF4
NGF
carnosic acid
antioxidant
Online Access:https://www.mdpi.com/1422-0067/20/7/1706

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