An unusual case of episodic quadriparesis

• Main Authors: Mukut Roy, Pranab Kumar Sahana, Nilanjan Sengupta, Chanchal Das, Ranen Dasgupta
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2013-01-01
• Series: Indian Journal of Endocrinology and Metabolism
• Subjects: Hypercalcemia; periodic paralysis; primary hyperparathyroidism; quadriparesis
• Online Access: http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=7;spage=234;epage=236;aulast=Roy

The natural history of untreated asymptomatic primary hyperparathyroidism (PHPT) remains incompletely understood. Increased level of parathyroid hormone produces the characteristic biochemical phenotype of hypercalcemia, hypophosphatemia and the various clinical sequelae of chronic hypercalcemia. Periodic paralysis (PP) is a group of disorders of different etiologies with episodic, short-lived and hyporeflexic skeletal muscle weakness, with or without myotonia, but without sensory deficit and without loss of consciousness. However, PHPT has rare association with episodic quadriparesis mimicking as PP.