MDR1 in immunity: friend or foe?

MDR1 is an ATP-dependent transmembrane transporter primarily studied for its role in the detoxification of tissues and for its implication in resistance of tumor cells to chemotherapy treatment. Several studies also report on its expression on immune cells where it plays a protective role from xenob...

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Bibliographic Details
Main Authors: Marion Bossennec, Anthony Di Roio, Christophe Caux, Christine Ménétrier-Caux
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1499388