Functional Thyroid Follicular Cells Differentiation from Human-Induced Pluripotent Stem Cells in Suspension Culture

The replacement of regenerated thyroid follicular cells (TFCs) is a promising therapeutic strategy for patients with hypothyroidism. Here, we have succeeded in inducing functional TFCs from human-induced pluripotent stem cells (iPSCs) in scalable suspension culture. Differentiation of iPSCs with Act...

Full description

Bibliographic Details
Main Authors: Ayumi Arauchi, Katsuhisa Matsuura, Tatsuya Shimizu, Teruo Okano
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00103/full