Anaplastic large cell lymphoma

Anaplastic large cell lymphoma is defined by a proliferation of large pleomorphic blasts and a constant expression of the CD30 molecule on all neoplastic cells, and has been clinically subdivided into a primary form and a secondary form. We are presenting a case of 14-year-old boy with reddish-livid...

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Bibliographic Details
Main Authors: Tiodorović Jelica, Lazarević Viktor, Stanojević Milenko, Jovanović Dragan, Tiodorović-Živković Danica
Format: Article
Language:English
Published: Institute of Oncology, Sremska Kamenica, Serbia 2006-01-01
Series:Archive of Oncology
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Online Access:http://www.doiserbia.nb.rs/img/doi/0354-7310/2006/0354-73100602054T.pdf
Description
Summary:Anaplastic large cell lymphoma is defined by a proliferation of large pleomorphic blasts and a constant expression of the CD30 molecule on all neoplastic cells, and has been clinically subdivided into a primary form and a secondary form. We are presenting a case of 14-year-old boy with reddish-livid papules on the skin of right half of trunk that were confluent in the lower end into solid plaque with diameter 20 x 15 cm, and enlarged lymph nodes in axilla and on neck. Lesioned skin biopsy, biopsy of lymph node and bone marrow showed pleomorphic cells, strongly CD30, and ALK positive. In our patient diagnosis was reached on the basis of morphological and immunohistochemical characteristics.
ISSN:0354-7310