RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection

Bacterial stress responses are potential targets for new antimicrobials. Here, Avican et al. present global transcriptomes for 32 bacterial pathogens grown under 11 stress conditions, and identify common and unique regulatory responses, as well as processes participating in different stress response...

Full description

Bibliographic Details
Main Authors: Kemal Avican, Jehad Aldahdooh, Matteo Togninalli, A. K. M. Firoj Mahmud, Jing Tang, Karsten M. Borgwardt, Mikael Rhen, Maria Fällman
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23588-w
id doaj-528c32ad693d42ecb0d3a057d1175df3
record_format Article
spelling doaj-528c32ad693d42ecb0d3a057d1175df32021-06-06T11:13:59ZengNature Publishing GroupNature Communications2041-17232021-06-0112111410.1038/s41467-021-23588-wRNA atlas of human bacterial pathogens uncovers stress dynamics linked to infectionKemal Avican0Jehad Aldahdooh1Matteo Togninalli2A. K. M. Firoj Mahmud3Jing Tang4Karsten M. Borgwardt5Mikael Rhen6Maria Fällman7Department of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for Microbial Research (UCMR), Umeå UniversityInstitute for Molecular Medicine Finland (FIMM), University of HelsinkiDepartment for Biosystems Science and Engineering, ETH ZürichDepartment of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for Microbial Research (UCMR), Umeå UniversityInstitute for Molecular Medicine Finland (FIMM), University of HelsinkiDepartment for Biosystems Science and Engineering, ETH ZürichDepartment of Microbiology, Tumor and Cell Biology (MTC), Karolinska InstituteDepartment of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå Centre for Microbial Research (UCMR), Umeå UniversityBacterial stress responses are potential targets for new antimicrobials. Here, Avican et al. present global transcriptomes for 32 bacterial pathogens grown under 11 stress conditions, and identify common and unique regulatory responses, as well as processes participating in different stress responses.https://doi.org/10.1038/s41467-021-23588-w
collection DOAJ
language English
format Article
sources DOAJ
author Kemal Avican
Jehad Aldahdooh
Matteo Togninalli
A. K. M. Firoj Mahmud
Jing Tang
Karsten M. Borgwardt
Mikael Rhen
Maria Fällman
spellingShingle Kemal Avican
Jehad Aldahdooh
Matteo Togninalli
A. K. M. Firoj Mahmud
Jing Tang
Karsten M. Borgwardt
Mikael Rhen
Maria Fällman
RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection
Nature Communications
author_facet Kemal Avican
Jehad Aldahdooh
Matteo Togninalli
A. K. M. Firoj Mahmud
Jing Tang
Karsten M. Borgwardt
Mikael Rhen
Maria Fällman
author_sort Kemal Avican
title RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection
title_short RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection
title_full RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection
title_fullStr RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection
title_full_unstemmed RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection
title_sort rna atlas of human bacterial pathogens uncovers stress dynamics linked to infection
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-06-01
description Bacterial stress responses are potential targets for new antimicrobials. Here, Avican et al. present global transcriptomes for 32 bacterial pathogens grown under 11 stress conditions, and identify common and unique regulatory responses, as well as processes participating in different stress responses.
url https://doi.org/10.1038/s41467-021-23588-w
work_keys_str_mv AT kemalavican rnaatlasofhumanbacterialpathogensuncoversstressdynamicslinkedtoinfection
AT jehadaldahdooh rnaatlasofhumanbacterialpathogensuncoversstressdynamicslinkedtoinfection
AT matteotogninalli rnaatlasofhumanbacterialpathogensuncoversstressdynamicslinkedtoinfection
AT akmfirojmahmud rnaatlasofhumanbacterialpathogensuncoversstressdynamicslinkedtoinfection
AT jingtang rnaatlasofhumanbacterialpathogensuncoversstressdynamicslinkedtoinfection
AT karstenmborgwardt rnaatlasofhumanbacterialpathogensuncoversstressdynamicslinkedtoinfection
AT mikaelrhen rnaatlasofhumanbacterialpathogensuncoversstressdynamicslinkedtoinfection
AT mariafallman rnaatlasofhumanbacterialpathogensuncoversstressdynamicslinkedtoinfection
_version_ 1721394295200546816