Principles of Network Architecture Emerging from Comparisons of the Cerebral Cortex in Large and Small Brains.

The cerebral cortex retains its fundamental organization, layering, and input-output relations as it scales in volume over many orders of magnitude in mammals. How is its network architecture affected by size scaling? By comparing network organization of the mouse and rhesus macaque cortical connect...

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Main Author: Barbara L Finlay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5025234?pdf=render
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spelling doaj-526cd082991545029ac70817dbe2a6502021-07-02T07:24:05ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852016-09-01149e100255610.1371/journal.pbio.1002556Principles of Network Architecture Emerging from Comparisons of the Cerebral Cortex in Large and Small Brains.Barbara L FinlayThe cerebral cortex retains its fundamental organization, layering, and input-output relations as it scales in volume over many orders of magnitude in mammals. How is its network architecture affected by size scaling? By comparing network organization of the mouse and rhesus macaque cortical connectome derived from complete neuroanatomical tracing studies, a recent study in PLOS Biology shows that an exponential distance rule emerges that reveals the falloff in connection probability with distance in the two brains that in turn determines common organizational features.http://europepmc.org/articles/PMC5025234?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Barbara L Finlay
spellingShingle Barbara L Finlay
Principles of Network Architecture Emerging from Comparisons of the Cerebral Cortex in Large and Small Brains.
PLoS Biology
author_facet Barbara L Finlay
author_sort Barbara L Finlay
title Principles of Network Architecture Emerging from Comparisons of the Cerebral Cortex in Large and Small Brains.
title_short Principles of Network Architecture Emerging from Comparisons of the Cerebral Cortex in Large and Small Brains.
title_full Principles of Network Architecture Emerging from Comparisons of the Cerebral Cortex in Large and Small Brains.
title_fullStr Principles of Network Architecture Emerging from Comparisons of the Cerebral Cortex in Large and Small Brains.
title_full_unstemmed Principles of Network Architecture Emerging from Comparisons of the Cerebral Cortex in Large and Small Brains.
title_sort principles of network architecture emerging from comparisons of the cerebral cortex in large and small brains.
publisher Public Library of Science (PLoS)
series PLoS Biology
issn 1544-9173
1545-7885
publishDate 2016-09-01
description The cerebral cortex retains its fundamental organization, layering, and input-output relations as it scales in volume over many orders of magnitude in mammals. How is its network architecture affected by size scaling? By comparing network organization of the mouse and rhesus macaque cortical connectome derived from complete neuroanatomical tracing studies, a recent study in PLOS Biology shows that an exponential distance rule emerges that reveals the falloff in connection probability with distance in the two brains that in turn determines common organizational features.
url http://europepmc.org/articles/PMC5025234?pdf=render
work_keys_str_mv AT barbaralfinlay principlesofnetworkarchitectureemergingfromcomparisonsofthecerebralcortexinlargeandsmallbrains
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