Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex

Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex

Focal Adhesion Kinase (FAK) is a non-receptor kinase that plays an important role in many cellular processes: adhesion, proliferation, invasion, angiogenesis, metastasis and survival. Recently, we have shown that Roslin 2 or R2 (1-benzyl-15,3,5,7-tetraazatricyclo[3.3.1.1~3,7~]decane) compound disrup...

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Bibliographic Details
Main Authors: Vita M. Golubovskaya, Baotran Ho, Jeffrey Conroy, Song Liu, Dan Wang, William G. Cance
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Cancers
Subjects:
Focal Adhesion Kinase
p53
Mdm-2
Nutlin
gene expression profiling
microarrays
combination therapy
Online Access:http://www.mdpi.com/2072-6694/6/1/166

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http://www.mdpi.com/2072-6694/6/1/166

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