t-BHQ Provides Protection against Lead Neurotoxicity via Nrf2/HO-1 Pathway
The neurotoxicity of lead has been well established, and oxidative stress is strongly associated with lead-induced neurotoxicity. Nrf2 is important for protection against oxidative stress in many disease models. We applied t-BHQ, which is an Nrf2 activator, to investigate the possible role of Nrf2 i...
Main Authors: | Fang Ye, Xiaoyi Li, Lili Li, Jing Yuan, Jun Chen |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
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Series: | Oxidative Medicine and Cellular Longevity |
Online Access: | http://dx.doi.org/10.1155/2016/2075915 |
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