t-BHQ Provides Protection against Lead Neurotoxicity via Nrf2/HO-1 Pathway

The neurotoxicity of lead has been well established, and oxidative stress is strongly associated with lead-induced neurotoxicity. Nrf2 is important for protection against oxidative stress in many disease models. We applied t-BHQ, which is an Nrf2 activator, to investigate the possible role of Nrf2 i...

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Bibliographic Details
Main Authors: Fang Ye, Xiaoyi Li, Lili Li, Jing Yuan, Jun Chen
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/2075915