Towards pathway‐centric cancer therapies via pharmacogenomic profiling analysis of ERK signalling pathway

Towards pathway‐centric cancer therapies via pharmacogenomic profiling analysis of ERK signalling pathway

Abstract BackgroundGenomic heterogeneity in human cancers complicates gene‐centric personalized medicine. Malignant tumors often share a core group of pathways that are perturbed by diverse genetic mutations. Therefore, one possible solution to overcome the heterogeneity challenge is a shift from ge...

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Bibliographic Details
Main Authors: Haiyun Wang, Xiaoqi Zheng, Teng Fei, Jinzeng Wang, Xujuan Li, Yin Liu, Fan Zhang
Format: Article
Language:English
Published: Wiley 2015-12-01
Series:Clinical and Translational Medicine
Subjects:
Personalized medicine
ERK signalling pathway
Pathway
Cancer therapies
Pharmacogenomic
Online Access:https://doi.org/10.1186/s40169-015-0066-1

Internet

https://doi.org/10.1186/s40169-015-0066-1

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