Mass spectrometry imaging for early discovery and development of cancer drugs

Mass spectrometry imaging for early discovery and development of cancer drugs

A drug delivery system (DDS) is a method for delivering a drug to its site of action in the body, with the goal of achieving therapeutic benefits while reducing adverse effects. Pharmacokinetics (PK) and pharmacodynamics (PD) studies have been conducted to evaluate drug delivery, but these approache...

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Bibliographic Details
Main Authors: Masahiro Yasunaga, Shino Manabe, Masaru Furuta, Koretsugu Ogata, Yoshikatsu Koga, Hiroki Takashima, Toshirou Nishida, Yasuhiro Matsumura
Format: Article
Language:English
Published: American Institute of Mathematical Sciences 2018-04-01
Series:AIMS Medical Science
Subjects:
drug discovery and development
molecular imaging
mass spectrometry imaging (MSI)
drug delivery system (DDS)
antibody-drug conjugate (ADC)
MALDI (matrix-associated laser desorption/ionization)
electrospray ionization (ESI)
mass microscope
Online Access:http://www.aimspress.com/medicalScience/article/1934/fulltext.html

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