A doxycycline-inducible C17.2 neural stem cell-based combination of differentiation and suicide gene therapy for an in vitro tumorigenic C6 glioma model

A doxycycline-inducible C17.2 neural stem cell-based combination of differentiation and suicide gene therapy for an in vitro tumorigenic C6 glioma model

Neural stem cell (NSC)-based gene therapies have been recently developed as effective strategies for treating brain tumors through inherent tumor tropism. However, this methodology has two considerable challenges: preventing NSCs from dying from the therapeutic agents encoded by their equipped genes...

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Bibliographic Details
Main Authors: Inn-Ray Chu, Rong-Long Pan, Chung-Shi Yang, Li-Chen Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
neural stem cell
herpes simplex type 1 thymidine kinase
differentiation therapy
ganciclovir
suicide gene therapy
connexin-43
Online Access:http://dx.doi.org/10.1080/13102818.2020.1804449

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