Comparison of commercially available media for hepatic differentiation and hepatocyte maintenance.
Human hepatocytes are essential materials in pharmaceutical researches. Not only primary human hepatocytes (PHH) but also human iPS cell-derived hepatocyte-like cells (human iPS-HLCs) are expected to be applied as materials for pharmaceutical researches. To date, several culture media have been deve...
Main Authors: | Yukiko Toba, Sayaka Deguchi, Natsumi Mimura, Ayaka Sakamoto, Kazuo Harada, Kazumasa Hirata, Kazuo Takayama, Hiroyuki Mizuguchi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0229654 |
Similar Items
-
In Vitro Model for a Drug Assessment of Cytochrome P450 Family 3 Subfamily A Member 4 Substrates Using Human Induced Pluripotent Stem Cells and Genome Editing Technology
by: Sayaka Deguchi, et al.
Published: (2021-08-01) -
Establishment of SLC15A1/PEPT1-Knockout Human-Induced Pluripotent Stem Cell Line for Intestinal Drug Absorption Studies
by: Kanae Kawai, et al.
Published: (2020-06-01) -
Tolloid‐Like 1 Negatively Regulates Hepatic Differentiation of Human Induced Pluripotent Stem Cells Through Transforming Growth Factor Beta Signaling
by: Ayumi Kiso, et al.
Published: (2020-02-01) -
Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells
by: Emi Sano, et al.
Published: (2021-05-01) -
Efficient Generation of Small Intestinal Epithelial-like Cells from Human iPSCs for Drug Absorption and Metabolism Studies
by: Ryosuke Negoro, et al.
Published: (2018-12-01)