Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit.

Dysfunction of the blood-brain barrier in postoperative delirium patients, referring to the axonal damage biomarker phosphorylated neurofilament heavy subunit.

BACKGROUND:Delirium is the most common postoperative complication of the central nervous system (CNS) that can trigger long-term cognitive impairment. Its underlying mechanism is not fully understood, but the dysfunction of the blood-brain barrier (BBB) has been implicated. The serum levels of the a...

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Bibliographic Details
Main Authors: Kazuhito Mietani, Masahiko Sumitani, Toru Ogata, Nobutake Shimojo, Reo Inoue, Hiroaki Abe, Gaku Kawamura, Yoshitsugu Yamada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222721

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https://doi.org/10.1371/journal.pone.0222721

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