The Health & Economic Disparities of Congenital Musculoskeletal Disease Worldwide: An Analysis of 25 Years (1992-2017)

Background: Large disparities exist in congenital musculoskeletal disease burden worldwide. The purpose of this study is to examine and quantify the health and economic disparities of congenital musculoskeletal disease by country income level from 1992 to 2017. Methods : The Global Burden of Disease...

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Main Authors: Kush S. Mody BS, Jeffrey Henstenburg MD, Martin J. Herman MD
Format: Article
Language:English
Published: SAGE Publishing 2021-02-01
Series:Global Pediatric Health
Online Access:https://doi.org/10.1177/2333794X21994998
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spelling doaj-52367804a7724f988c2aad746f958ea22021-02-28T06:03:59ZengSAGE PublishingGlobal Pediatric Health2333-794X2021-02-01810.1177/2333794X21994998The Health & Economic Disparities of Congenital Musculoskeletal Disease Worldwide: An Analysis of 25 Years (1992-2017)Kush S. Mody BS0Jeffrey Henstenburg MD1Martin J. Herman MD2Drexel University College of Medicine, Philadelphia, PA, USAThomas Jefferson University Hospital, Philadelphia, PA, USASt. Christopher’s Hospital for Children, Philadelphia, PA, USABackground: Large disparities exist in congenital musculoskeletal disease burden worldwide. The purpose of this study is to examine and quantify the health and economic disparities of congenital musculoskeletal disease by country income level from 1992 to 2017. Methods : The Global Burden of Disease database was queried for information on disease burden attributed to “congenital musculoskeletal and limb anomalies” from 1992 to 2017. Gross national income per capita was extracted from the World Bank website. Nonparametric Kruskal–Wallis tests were used to compare morbidity and mortality across years and income levels. The number of avertable DALYs was converted to an economic disparity using the human-capital and value of a statistical life approach. Results : From 1992 to 2017, a significant decrease in deaths/100 000 was observed only in upper-middle and high income countries. Northern Africa, the Middle East, and Eastern Europe were disproportionately affected. If the burden of disease in low- and middle- income countries (LMICs) was equivalent to that in high income countries (HICs), 10% of all DALYs and 70% of all deaths attributable to congenital musculoskeletal disease in LMICs could be averted. This equates to an economic disparity of about $2 billion to $3 billion (in 2020 $USD). Conclusion : Considerable inequity exists in the burden of congenital musculoskeletal disease worldwide and there has been no change over the last 25 years in total disease burden and geographical distribution. By reducing the disease burden in LMICs to rates found in HICs, a large proportion of the health and economic consequences could be averted.https://doi.org/10.1177/2333794X21994998
collection DOAJ
language English
format Article
sources DOAJ
author Kush S. Mody BS
Jeffrey Henstenburg MD
Martin J. Herman MD
spellingShingle Kush S. Mody BS
Jeffrey Henstenburg MD
Martin J. Herman MD
The Health & Economic Disparities of Congenital Musculoskeletal Disease Worldwide: An Analysis of 25 Years (1992-2017)
Global Pediatric Health
author_facet Kush S. Mody BS
Jeffrey Henstenburg MD
Martin J. Herman MD
author_sort Kush S. Mody BS
title The Health & Economic Disparities of Congenital Musculoskeletal Disease Worldwide: An Analysis of 25 Years (1992-2017)
title_short The Health & Economic Disparities of Congenital Musculoskeletal Disease Worldwide: An Analysis of 25 Years (1992-2017)
title_full The Health & Economic Disparities of Congenital Musculoskeletal Disease Worldwide: An Analysis of 25 Years (1992-2017)
title_fullStr The Health & Economic Disparities of Congenital Musculoskeletal Disease Worldwide: An Analysis of 25 Years (1992-2017)
title_full_unstemmed The Health & Economic Disparities of Congenital Musculoskeletal Disease Worldwide: An Analysis of 25 Years (1992-2017)
title_sort health & economic disparities of congenital musculoskeletal disease worldwide: an analysis of 25 years (1992-2017)
publisher SAGE Publishing
series Global Pediatric Health
issn 2333-794X
publishDate 2021-02-01
description Background: Large disparities exist in congenital musculoskeletal disease burden worldwide. The purpose of this study is to examine and quantify the health and economic disparities of congenital musculoskeletal disease by country income level from 1992 to 2017. Methods : The Global Burden of Disease database was queried for information on disease burden attributed to “congenital musculoskeletal and limb anomalies” from 1992 to 2017. Gross national income per capita was extracted from the World Bank website. Nonparametric Kruskal–Wallis tests were used to compare morbidity and mortality across years and income levels. The number of avertable DALYs was converted to an economic disparity using the human-capital and value of a statistical life approach. Results : From 1992 to 2017, a significant decrease in deaths/100 000 was observed only in upper-middle and high income countries. Northern Africa, the Middle East, and Eastern Europe were disproportionately affected. If the burden of disease in low- and middle- income countries (LMICs) was equivalent to that in high income countries (HICs), 10% of all DALYs and 70% of all deaths attributable to congenital musculoskeletal disease in LMICs could be averted. This equates to an economic disparity of about $2 billion to $3 billion (in 2020 $USD). Conclusion : Considerable inequity exists in the burden of congenital musculoskeletal disease worldwide and there has been no change over the last 25 years in total disease burden and geographical distribution. By reducing the disease burden in LMICs to rates found in HICs, a large proportion of the health and economic consequences could be averted.
url https://doi.org/10.1177/2333794X21994998
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