ROBUST CONTROL OF END-TIDAL CO<sub>2</sub> USING THE H<sub>&infin;</sub> LOOP-SHAPING APPROACH

Mechanically ventilated patients require appropriate settings of respiratory control variables to maintain acceptable gas exchange. To control the carbon dioxide (CO<sub>2</sub>) level effectively and automatically, system identification based on a human subject was performed using a lin...

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Bibliographic Details
Main Authors: Anake Pomprapa, Berno Misgeld, Verónica Sorgato, André Stollenwerk, Marian Walter, Steffen Leonhardt
Format: Article
Language:English
Published: CTU Central Library 2013-12-01
Series:Acta Polytechnica
Online Access:https://ojs.cvut.cz/ojs/index.php/ap/article/view/2024
Description
Summary:Mechanically ventilated patients require appropriate settings of respiratory control variables to maintain acceptable gas exchange. To control the carbon dioxide (CO<sub>2</sub>) level effectively and automatically, system identification based on a human subject was performed using a linear affine model and a nonlinear Hammerstein structure. Subsequently, a robust controller was designed using the H<sub>∞</sub> loop-shaping approach, which synthesizes the optimal controller based on a specific objective by achieving stability with guaranteed performance. For demonstration purposes, the closed-loop control ventilation system was successfully tested in a human volunteer. The experimental results indicate that the blood CO<sub>2</sub> level may indeed be controlled noninvasively by measuring end-tidal CO<sub>2</sub> from expired air. Keeping the limited amount of experimental data in mind, we conclude that H<sub>∞</sub> loop-shaping may be a promising technique for control of mechanical ventilation in patients with respiratory insufficiency.
ISSN:1210-2709
1805-2363