Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates.

Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates.

Cryptococcus spp. are responsible for around one million cases of meningitis every year. Fluconazole (FLU) is commonly used in the treatment of cryptococcosis, mainly in immunocompromised patients and the resistance is usually reported after long periods of treatment. In this study, the morphologica...

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Bibliographic Details
Main Authors: Suélen Andreia eRossi, Nuria eTrevijano-Contador, Liliana eScorzoni, Ana Cecilia eMesa Arango, Haroldo eOliveira, Karen eWerther, Tania Freitas Raso, Maria José Soares Mendes-Giannini, Oscar eZaragoza, Ana Marisa eFusco-Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Microbiology
Subjects:
Fluconazole
Virulence
Resistance
Cryptococcus spp.
Galleria mellonella
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00153/full

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