The abundance of Akkermansia muciniphila and its relationship with sulphated colonic mucins in health and ulcerative colitis
Abstract Akkermansia muciniphila utilises colonic mucin as its substrate. Abundance is reduced in ulcerative colitis (UC), as is the relative proportion of sulphated mucin in the mucus gel layer (MGL). It is unknown if these phenomena are related, however reduced sulphated mucins could contribute to...
Main Authors: | Helen Earley, Grainne Lennon, Áine Balfe, J. Calvin Coffey, Desmond C. Winter, P. Ronan O’Connell |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-51878-3 |
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