Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient

Papillary thyroid carcinoma is the most common endocrine cancer in the paediatric population. Although the disease is diagnosed at a later stage, the prognosis is favourable. When these patients present with lymph nodal and/or pulmonary metastases, they may be initially confused for infectious disea...

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Main Authors: Nthabiseng Ellen Mothata, Takalani Gidion Morulana, Nyaweleni Tshifularo, Phumudzo Bridgett Nemutaduni, Nozipho Elizabeth Nyakale, Moshawa Calvin Khaba
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2021/6655491
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spelling doaj-52109c04502d4ab4be5c211ae37911082021-02-15T12:52:57ZengHindawi LimitedCase Reports in Endocrinology2090-65012090-651X2021-01-01202110.1155/2021/66554916655491Metastatic Papillary Thyroid Carcinoma in a Paediatric PatientNthabiseng Ellen Mothata0Takalani Gidion Morulana1Nyaweleni Tshifularo2Phumudzo Bridgett Nemutaduni3Nozipho Elizabeth Nyakale4Moshawa Calvin Khaba5Department of Anatomical Pathology, Dr George Mukhari Academic Laboratory, National Health Laboratory Services, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South AfricaDepartment of Paediatric Surgery, Dr George Mukhari Academic Hospital, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South AfricaDepartment of Paediatric Surgery, Dr George Mukhari Academic Hospital, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South AfricaDepartment of Nuclear Medicine, Dr George Mukhari Academic Hospital, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South AfricaDepartment of Nuclear Medicine, Dr George Mukhari Academic Hospital, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South AfricaDepartment of Anatomical Pathology, Dr George Mukhari Academic Laboratory, National Health Laboratory Services, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South AfricaPapillary thyroid carcinoma is the most common endocrine cancer in the paediatric population. Although the disease is diagnosed at a later stage, the prognosis is favourable. When these patients present with lymph nodal and/or pulmonary metastases, they may be initially confused for infectious diseases such as tuberculosis. Therefore, thorough clinical assessment including radiology and microbiological and histopathological assessment is important for early and correct diagnosis. We report an 11-year-old female patient who presented with cervical lymphadenopathy and the histopathological assessment confirmed metastatic papillary thyroid carcinoma. Subsequent radiological investigation revealed further metastasis to the lung. This manuscript highlights the difficulties that might be encountered in the initial management of paediatric PTC which present atypically.http://dx.doi.org/10.1155/2021/6655491
collection DOAJ
language English
format Article
sources DOAJ
author Nthabiseng Ellen Mothata
Takalani Gidion Morulana
Nyaweleni Tshifularo
Phumudzo Bridgett Nemutaduni
Nozipho Elizabeth Nyakale
Moshawa Calvin Khaba
spellingShingle Nthabiseng Ellen Mothata
Takalani Gidion Morulana
Nyaweleni Tshifularo
Phumudzo Bridgett Nemutaduni
Nozipho Elizabeth Nyakale
Moshawa Calvin Khaba
Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient
Case Reports in Endocrinology
author_facet Nthabiseng Ellen Mothata
Takalani Gidion Morulana
Nyaweleni Tshifularo
Phumudzo Bridgett Nemutaduni
Nozipho Elizabeth Nyakale
Moshawa Calvin Khaba
author_sort Nthabiseng Ellen Mothata
title Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient
title_short Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient
title_full Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient
title_fullStr Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient
title_full_unstemmed Metastatic Papillary Thyroid Carcinoma in a Paediatric Patient
title_sort metastatic papillary thyroid carcinoma in a paediatric patient
publisher Hindawi Limited
series Case Reports in Endocrinology
issn 2090-6501
2090-651X
publishDate 2021-01-01
description Papillary thyroid carcinoma is the most common endocrine cancer in the paediatric population. Although the disease is diagnosed at a later stage, the prognosis is favourable. When these patients present with lymph nodal and/or pulmonary metastases, they may be initially confused for infectious diseases such as tuberculosis. Therefore, thorough clinical assessment including radiology and microbiological and histopathological assessment is important for early and correct diagnosis. We report an 11-year-old female patient who presented with cervical lymphadenopathy and the histopathological assessment confirmed metastatic papillary thyroid carcinoma. Subsequent radiological investigation revealed further metastasis to the lung. This manuscript highlights the difficulties that might be encountered in the initial management of paediatric PTC which present atypically.
url http://dx.doi.org/10.1155/2021/6655491
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