Modulating autophagy in mesenchymal stem cells effectively protects against hypoxia- or ischemia-induced injury
Abstract In mammals, a basal level of autophagy, a self-eating cellular process, degrades cytosolic proteins and subcellular organelles in lysosomes to provide energy, recycles the cytoplasmic components, and regenerates cellular building blocks; thus, autophagy maintains cellular and tissue homeost...
Main Authors: | Chenxia Hu, Lingfei Zhao, Daxian Wu, Lanjuan Li |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-04-01
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Series: | Stem Cell Research & Therapy |
Online Access: | http://link.springer.com/article/10.1186/s13287-019-1225-x |
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