A novel bi-directional promoter system allows tunable recombinant protein production in Pichia pastoris

Abstract Background The methylotrophic yeast Pichia pastoris is a well-studied host organism for recombinant protein production, which is usually regulated either by a constitutive promoter (e.g. promoter of glyceraldehyde-3-phosphate dehydrogenase; PGAP) or an inducible promoter (e.g. promoter of a...

Full description

Bibliographic Details
Main Authors: Vignesh Rajamanickam, Karl Metzger, Christian Schmid, Oliver Spadiut
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-017-0768-8

Similar Items