A novel bi-directional promoter system allows tunable recombinant protein production in Pichia pastoris
Abstract Background The methylotrophic yeast Pichia pastoris is a well-studied host organism for recombinant protein production, which is usually regulated either by a constitutive promoter (e.g. promoter of glyceraldehyde-3-phosphate dehydrogenase; PGAP) or an inducible promoter (e.g. promoter of a...
Main Authors: | Vignesh Rajamanickam, Karl Metzger, Christian Schmid, Oliver Spadiut |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-09-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12934-017-0768-8 |
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