Replication-Competent Foamy Virus Vaccine Vectors as Novel Epitope Scaffolds for Immunotherapy.

The use of whole viruses as antigen scaffolds is a recent development in vaccination that improves immunogenicity without the need for additional adjuvants. Previous studies highlighted the potential of foamy viruses (FVs) in prophylactic vaccination and gene therapy. Replication-competent FVs can t...

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Bibliographic Details
Main Authors: Janet Lei, Wolfram Osen, Adriane Gardyan, Agnes Hotz-Wagenblatt, Guochao Wei, Lutz Gissmann, Stefan Eichmüller, Martin Löchelt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0138458