Disruption of the RNA modifications that target the ribosome translation machinery in human cancer
Abstract Genetic and epigenetic changes deregulate RNA and protein expression in cancer cells. In this regard, tumors exhibit an abnormal proteome in comparison to the corresponding normal tissues. Translation control is a crucial step in the regulation of gene expression regulation under normal and...
Main Authors: | Maxime Janin, Laia Coll-SanMartin, Manel Esteller |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12943-020-01192-8 |
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