An altered cytotoxic program of CD8+ T-cells in HIV-infected patients despite HAART-induced viral suppression.

An altered cytotoxic program of CD8+ T-cells in HIV-infected patients despite HAART-induced viral suppression.

Despite the suppression of viral replication induced by the highly active anti-retroviral therapy (HAART), an increased immune activation and inflammatory state persists in HIV-infected patients, contributing to lower treatment response and immune reconstitution, and development of non-AIDS conditio...

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Bibliographic Details
Main Authors:	Federico Perdomo-Celis, Paula A Velilla, Natalia A Taborda, María Teresa Rugeles
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2019-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0210540

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