Aβ-globulomers are formed independently of the fibril pathway

Aβ-globulomers are formed independently of the fibril pathway

Soluble Aβ-oligomers are currently discussed as the major causative species for the development of Alzheimer's disease (AD). Consequently, the β-amyloid cascade hypothesis was extended by Aβ-oligomers and their central neuropathogenic role in AD. However, the molecular structure of Aβ-oligomers...

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Bibliographic Details
Main Authors: Gerald P. Gellermann, Helga Byrnes, Andreas Striebinger, Kathrin Ullrich, Reinhold Mueller, Heinz Hillen, Stefan Barghorn
Format: Article
Language:English
Published: Elsevier 2008-05-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Dementia, Amyloid β-protein
Oligomers
Fibrils
Conformational diseases
Monocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000090

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