Computing highly correlated positions using mutual information and graph theory for G protein-coupled receptors.

Computing highly correlated positions using mutual information and graph theory for G protein-coupled receptors.

G protein-coupled receptors (GPCRs) are a superfamily of seven transmembrane-spanning proteins involved in a wide array of physiological functions and are the most common targets of pharmaceuticals. This study aims to identify a cohort or clique of positions that share high mutual information. Using...

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Bibliographic Details
Main Authors: Sarosh N Fatakia, Stefano Costanzi, Carson C Chow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19262747/?tool=EBI

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