A Versatile Model of Microfluidic Perifusion System for the Evaluation of C-Peptide Secretion Profiles: Comparison Between Human Pancreatic Islets and HLSC-Derived Islet-Like Structures

A Versatile Model of Microfluidic Perifusion System for the Evaluation of C-Peptide Secretion Profiles: Comparison Between Human Pancreatic Islets and HLSC-Derived Islet-Like Structures

A robust and easy-to-use tool for the ex vivo dynamic evaluation of pancreatic islet (PI) function is essential for further development of novel cell-based therapeutic approaches to treating diabetes. Here, we developed four different glucose perifusion protocols (GPPs) in a microfluidic perifusion...

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Bibliographic Details
Main Authors: Yonathan Gomez, Victor Navarro-Tableros, Ciro Tetta, Giovanni Camussi, Maria Felice Brizzi
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomedicines
Subjects:
microfluidic
perifusion
c-peptide
human pancreatic islets
obese
t2dm
hlsc-ils
Online Access:https://www.mdpi.com/2227-9059/8/2/26

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