Protein Requirements during Aging
Protein recommendations for elderly, both men and women, are based on nitrogen balance studies. They are set at 0.66 and 0.8 g/kg/day as the estimated average requirement (EAR) and recommended dietary allowance (RDA), respectively, similar to young adults. This recommendation is based on single line...
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doaj-51b8f540f62346408b6e905c8e8d19122020-11-24T21:05:42ZengMDPI AGNutrients2072-66432016-08-018849210.3390/nu8080492nu8080492Protein Requirements during AgingGlenda Courtney-Martin0Ronald O. Ball1Paul B. Pencharz2Rajavel Elango3Research Institute, Hospital for Sick Children, Toronto, ON M5G 1X8, CanadaAgricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2R3, CanadaResearch Institute, Hospital for Sick Children, Toronto, ON M5G 1X8, CanadaDepartment of Pediatrics, University of British Columbia, Vancouver, BC V6H 3V4, CanadaProtein recommendations for elderly, both men and women, are based on nitrogen balance studies. They are set at 0.66 and 0.8 g/kg/day as the estimated average requirement (EAR) and recommended dietary allowance (RDA), respectively, similar to young adults. This recommendation is based on single linear regression of available nitrogen balance data obtained at test protein intakes close to or below zero balance. Using the indicator amino acid oxidation (IAAO) method, we estimated the protein requirement in young adults and in both elderly men and women to be 0.9 and 1.2 g/kg/day as the EAR and RDA, respectively. This suggests that there is no difference in requirement on a gender basis or on a per kg body weight basis between younger and older adults. The requirement estimates however are ~40% higher than the current protein recommendations on a body weight basis. They are also 40% higher than our estimates in young men when calculated on the basis of fat free mass. Thus, current recommendations may need to be re-assessed. Potential rationale for this difference includes a decreased sensitivity to dietary amino acids and increased insulin resistance in the elderly compared with younger individuals.http://www.mdpi.com/2072-6643/8/8/492elderlyproteinrequirementsindicator amino acid oxidation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Glenda Courtney-Martin Ronald O. Ball Paul B. Pencharz Rajavel Elango |
spellingShingle |
Glenda Courtney-Martin Ronald O. Ball Paul B. Pencharz Rajavel Elango Protein Requirements during Aging Nutrients elderly protein requirements indicator amino acid oxidation |
author_facet |
Glenda Courtney-Martin Ronald O. Ball Paul B. Pencharz Rajavel Elango |
author_sort |
Glenda Courtney-Martin |
title |
Protein Requirements during Aging |
title_short |
Protein Requirements during Aging |
title_full |
Protein Requirements during Aging |
title_fullStr |
Protein Requirements during Aging |
title_full_unstemmed |
Protein Requirements during Aging |
title_sort |
protein requirements during aging |
publisher |
MDPI AG |
series |
Nutrients |
issn |
2072-6643 |
publishDate |
2016-08-01 |
description |
Protein recommendations for elderly, both men and women, are based on nitrogen balance studies. They are set at 0.66 and 0.8 g/kg/day as the estimated average requirement (EAR) and recommended dietary allowance (RDA), respectively, similar to young adults. This recommendation is based on single linear regression of available nitrogen balance data obtained at test protein intakes close to or below zero balance. Using the indicator amino acid oxidation (IAAO) method, we estimated the protein requirement in young adults and in both elderly men and women to be 0.9 and 1.2 g/kg/day as the EAR and RDA, respectively. This suggests that there is no difference in requirement on a gender basis or on a per kg body weight basis between younger and older adults. The requirement estimates however are ~40% higher than the current protein recommendations on a body weight basis. They are also 40% higher than our estimates in young men when calculated on the basis of fat free mass. Thus, current recommendations may need to be re-assessed. Potential rationale for this difference includes a decreased sensitivity to dietary amino acids and increased insulin resistance in the elderly compared with younger individuals. |
topic |
elderly protein requirements indicator amino acid oxidation |
url |
http://www.mdpi.com/2072-6643/8/8/492 |
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