Anti-Inflammatory Effect of Charantadiol A, Isolated from Wild Bitter Melon Leaf, on Heat-Inactivated <i>Porphyromonas gingivalis</i>-Stimulated THP-1 Monocytes and a Periodontitis Mouse Model

Anti-Inflammatory Effect of Charantadiol A, Isolated from Wild Bitter Melon Leaf, on Heat-Inactivated <i>Porphyromonas gingivalis</i>-Stimulated THP-1 Monocytes and a Periodontitis Mouse Model

<i>Porphyromonas gingivalis</i> has been identified as one of the major periodontal pathogens. Activity-directed fractionation and purification processes were employed to identify bioactive compounds from bitter melon leaf. Ethanolic extract of bitter melon leaf was separated into five s...

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Bibliographic Details
Main Authors: Tzung-Hsun Tsai, Chi-I Chang, Ya-Ling Hung, Wen-Cheng Huang, Hsiang Chang, Yueh-Hsiung Kuo, Jong-Ho Chyuan, Lu-Te Chuang, Po-Jung Tsai
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
anti-inflammation
bitter melon
charantadiol A
<i>Porphyromonas gingivalis</i>
Online Access:https://www.mdpi.com/1420-3049/26/18/5651

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