Diversification of the Caenorhabditis heat shock response by Helitron transposable elements

Diversification of the Caenorhabditis heat shock response by Helitron transposable elements

Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress. Remarkably, we found that substantial numbers o...

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Bibliographic Details
Main Authors: Jacob M Garrigues, Brian V Tsu, Matthew D Daugherty, Amy E Pasquinelli
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
heat shock
HSF-1
transposons
Caenorhabditis
Online Access:https://elifesciences.org/articles/51139

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