Diversification of the Caenorhabditis heat shock response by Helitron transposable elements

Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress. Remarkably, we found that substantial numbers o...

Full description

Bibliographic Details
Main Authors: Jacob M Garrigues, Brian V Tsu, Matthew D Daugherty, Amy E Pasquinelli
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/51139