2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine
Starting from N-methyl-1-[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine (1) target compound 2 is prepared in a mild, direct alkylation approach with 2-fluoroethyl trifluoromethanesulfonate.
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MDPI AG
2015-06-01
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| Series: | Molbank |
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| Online Access: | http://www.mdpi.com/1422-8599/2015/2/M862 |
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doaj-51a8459727d04de6b09d8130816eeb272020-11-24T22:13:28ZengMDPI AGMolbank1422-85992015-06-0120152M86210.3390/M862M8622-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamineCatharina Neudorfer0Karem Shanab1Wolfgang Holzer2Christina Rami-Mark3Markus Mitterhauser4Wolfgang Wadsak5Helmut Spreitzer6Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDivision of Drug Synthesis, Department of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, Althanstraße 14, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDivision of Drug Synthesis, Department of Pharmaceutical Chemistry, Faculty of Life Sciences, University of Vienna, Althanstraße 14, 1090 Vienna, AustriaStarting from N-methyl-1-[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine (1) target compound 2 is prepared in a mild, direct alkylation approach with 2-fluoroethyl trifluoromethanesulfonate.http://www.mdpi.com/1422-8599/2015/2/M862NETPETPHOXI |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Catharina Neudorfer Karem Shanab Wolfgang Holzer Christina Rami-Mark Markus Mitterhauser Wolfgang Wadsak Helmut Spreitzer |
| spellingShingle |
Catharina Neudorfer Karem Shanab Wolfgang Holzer Christina Rami-Mark Markus Mitterhauser Wolfgang Wadsak Helmut Spreitzer 2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine Molbank NET PET PHOXI |
| author_facet |
Catharina Neudorfer Karem Shanab Wolfgang Holzer Christina Rami-Mark Markus Mitterhauser Wolfgang Wadsak Helmut Spreitzer |
| author_sort |
Catharina Neudorfer |
| title |
2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine |
| title_short |
2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine |
| title_full |
2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine |
| title_fullStr |
2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine |
| title_full_unstemmed |
2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine |
| title_sort |
2-fluoro-n-methyl-n-{[(3s*,4s*)-4-(2-methylphenoxy)-3,4-dihydro-1h-isochromen-3-yl]methyl}ethanamine |
| publisher |
MDPI AG |
| series |
Molbank |
| issn |
1422-8599 |
| publishDate |
2015-06-01 |
| description |
Starting from N-methyl-1-[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine (1) target compound 2 is prepared in a mild, direct alkylation approach with 2-fluoroethyl trifluoromethanesulfonate. |
| topic |
NET PET PHOXI |
| url |
http://www.mdpi.com/1422-8599/2015/2/M862 |
| work_keys_str_mv |
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| _version_ |
1725800935622443008 |