Bifurcations and Dynamics of the Rb-E2F Pathway Involving miR449
We focused on the gene regulative network involving Rb-E2F pathway and microRNAs (miR449) and studied the influence of time delay on the dynamical behaviors of Rb-E2F pathway by using Hopf bifurcation theory. It is shown that under certain assumptions the steady state of the delay model is asymptoti...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Hindawi-Wiley
2017-01-01
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Series: | Complexity |
Online Access: | http://dx.doi.org/10.1155/2017/1409865 |