Caffeine Neuroprotective Mechanism Against β-Amyloid Neurotoxicity in SHSY5Y Cell Line: Involvement of Adenosine, Ryanodine, and N-Methyl-D-Aspartate Receptors

Caffeine Neuroprotective Mechanism Against β-Amyloid Neurotoxicity in SHSY5Y Cell Line: Involvement of Adenosine, Ryanodine, and N-Methyl-D-Aspartate Receptors

Purpose: Some reports have shown neuroprotective effects of caffeine in several neurodegenerative disorders. However, its mechanism of action is not completely clear. Therefore, the aim of this study was to explore the interference of ryanodine, N-methyl-D-aspartate (NMDA) and adenosine modulators w...

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Bibliographic Details
Main Authors: Mojtaba Keshavarz, Majid Reza Farrokhi, Atena Amiri
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2017-12-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Caffeine
N-methyl-D-Aspartate
Adenosine
Dantrolene
β-amyloid
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-7-579.pdf

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