Expression of Ik6 and Ik8 Isoforms and Their Association with Relapse and Death in Mexican Children with Acute Lymphoblastic Leukemia.

Expression of the 6 and 8 dominant-negative Ikaros isoforms in pediatric patients with acute lymphoblastic leukemia has been associated with a high risk of relapse and death; due to these isoforms disrupting the differentiation and proliferation of lymphoid cells. The aim of this study was to know t...

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Main Authors: Adriana Reyes-León, Rocío Juárez-Velázquez, Alma Medrano-Hernández, Teresa Cuenca-Roldán, Consuelo Salas-Labadía, María Del Pilar Navarrete-Meneses, Roberto Rivera-Luna, Gerardo López-Hernández, Rogelio Paredes-Aguilera, Patricia Pérez-Vera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0130756