Toughening in electrospun fibrous scaffolds

Toughening in electrospun fibrous scaffolds

Electrospun scaffolds mimic the microstructure of structural collagenous tissues and have been widely used in tissue engineering applications. Both brittle cracking and ductile failure have been observed in scaffolds with similarly random fibrous morphology. Finite element analysis can...

Full description

Bibliographic Details
Main Authors: C. T. Koh, M. L. Oyen
Format: Article
Language:English
Published: AIP Publishing LLC 2015-01-01
Series:APL Materials
Online Access:http://dx.doi.org/10.1063/1.4901450
id doaj-518816e69c0f4aca962149065ed2ce0a
record_format Article
spelling doaj-518816e69c0f4aca962149065ed2ce0a2020-11-24T23:52:41ZengAIP Publishing LLCAPL Materials2166-532X2015-01-0131014908014908-510.1063/1.4901450008595APMToughening in electrospun fibrous scaffoldsC. T. Koh0M. L. Oyen1Cambridge University Engineering Department, Trumpington Street, Cambridge CB2 1PZ, United KingdomCambridge University Engineering Department, Trumpington Street, Cambridge CB2 1PZ, United Kingdom Electrospun scaffolds mimic the microstructure of structural collagenous tissues and have been widely used in tissue engineering applications. Both brittle cracking and ductile failure have been observed in scaffolds with similarly random fibrous morphology. Finite element analysis can be used to qualitatively examine the mechanics of these differing failure mechanisms. The finite element modeling demonstrates that the noncontinuum deformation of the network structure results in fiber bundle formation and material toughening. Such toughening is accommodated by varying fiber properties, including allowing large failure strains and progressive damage of the fibers. http://dx.doi.org/10.1063/1.4901450
collection DOAJ
language English
format Article
sources DOAJ
author C. T. Koh
M. L. Oyen
spellingShingle C. T. Koh
M. L. Oyen
Toughening in electrospun fibrous scaffolds
APL Materials
author_facet C. T. Koh
M. L. Oyen
author_sort C. T. Koh
title Toughening in electrospun fibrous scaffolds
title_short Toughening in electrospun fibrous scaffolds
title_full Toughening in electrospun fibrous scaffolds
title_fullStr Toughening in electrospun fibrous scaffolds
title_full_unstemmed Toughening in electrospun fibrous scaffolds
title_sort toughening in electrospun fibrous scaffolds
publisher AIP Publishing LLC
series APL Materials
issn 2166-532X
publishDate 2015-01-01
description Electrospun scaffolds mimic the microstructure of structural collagenous tissues and have been widely used in tissue engineering applications. Both brittle cracking and ductile failure have been observed in scaffolds with similarly random fibrous morphology. Finite element analysis can be used to qualitatively examine the mechanics of these differing failure mechanisms. The finite element modeling demonstrates that the noncontinuum deformation of the network structure results in fiber bundle formation and material toughening. Such toughening is accommodated by varying fiber properties, including allowing large failure strains and progressive damage of the fibers.
url http://dx.doi.org/10.1063/1.4901450
work_keys_str_mv AT ctkoh tougheninginelectrospunfibrousscaffolds
AT mloyen tougheninginelectrospunfibrousscaffolds
_version_ 1725472581897682944

Similar Items