3D mesh processing using GAMer 2 to enable reaction-diffusion simulations in realistic cellular geometries.
Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed geometries. Enabling such simulations requires watertight meshin...
Main Authors: | Christopher T Lee, Justin G Laughlin, Nils Angliviel de La Beaumelle, Rommie E Amaro, J Andrew McCammon, Ravi Ramamoorthi, Michael Holst, Padmini Rangamani |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-04-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1007756 |
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