Expression of hypoxic marker carbonic anhydrase IX predicts poor prognosis in resectable hepatocellular carcinoma.

Carbonic anhydrase IX (CA-IX), a hypoxia marker, correlates with tumor progression in a variety of human cancers. However, the role of CA-IX in hepatocellular carcinomas (HCCs) remains largely unknown. We examined the expression of 277 unifocal, resectable, primary HCC tumors using immunohistochemis...

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Bibliographic Details
Main Authors: Wei-Ju Huang, Yung-Ming Jeng, Hong-Shiee Lai, Iok-U Fong, Fang-Yu Bonnie Sheu, Po-Lin Lai, Ray-Hwang Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4349857?pdf=render