Novel Benzenesulfonate Scaffolds with a High Anticancer Activity and G2/M Cell Cycle Arrest

Novel Benzenesulfonate Scaffolds with a High Anticancer Activity and G2/M Cell Cycle Arrest

Sulfonates, unlike their derivatives, sulphonamides, have rarely been investigated for their anticancer activity. Unlike the well-known sulphonamides, esters are mainly used as convenient intermediates in a synthesis. Here, we present the first in-depth investigation of quinazoline sulfonates. A sma...

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Bibliographic Details
Main Authors: Katarzyna Malarz, Jacek Mularski, Michał Kuczak, Anna Mrozek-Wilczkiewicz, Robert Musiol
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
styrylquinazoline
sulfonic derivatives
anticancer activity
cell cycle inhibition
G2/M phase
apoptosis
Online Access:https://www.mdpi.com/2072-6694/13/8/1790

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